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Paper Reading Journals #8

Dementia risk analysis using temporal event modeling on a large real-world dataset

Basic Info

Item Content
Title Dementia risk analysis using temporal event modeling on a large real-world dataset
Journal Scientific Reports
Author R. Andrew Taylor, Aidan Gilson, Ling Chi, et al.
Year Published 2023
Link https://doi.org/10.1038/s41598-023-49330-8
Geography of Study USA
Area of Study Dementia, EHR

Description

(Including data and methods)

Data: 442,278 patients in New England health system. Method: (1) Temporal Event Analysis - Fisher’s Exact Test in Bonferroni & Bernoulli Trail (2) trajectory clustering (3) Dynamic Time Warping

Main Contribution

(Innovative method or Application) Innovation Type: Application innovation. This paper applied temporal statistical analysis to identify dementia-related risk events that occur prior to the onset of dementia. It combined temporal event modeling and clustering methods to uncover the time-dependent features of dementia progression. This approach may improve the explainability and interpretability of dementia occurrence.

Data Source

Emergency Department record in New England health system with n=442,278

Favorite Thing

This paper provides a potential modeling approach to trace dementia pathways before onset by incorporating temporal features. We may consider adopting this method in our future modeling framework.

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